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Secondary Myelofibrosis (SMF)
Prognostic Scores Calculator
Clinical Features
Age (years)
Constitutional Symptoms
Yes
No
N/A
Complete Blood Count
Hb < 11 g/dL
Yes
No
N/A
PLT < 150 x10
9
/L
Yes
No
N/A
Blasts ≥ 3%
Yes
No
N/A
Driver Mutation Status
CALR wildtype
Yes
No
N/A
Additional Myeloid Mutations
ASXL1 mutated without UTS mutations
ASXL1 mutated; U2AF1, TP53, and SRSF2 unmutated
Yes
No
N/A
U2AF1 and/or TP53 and/or SRSF2 (UTS) mutations
U2AF1, TP53, or SRSF2 mutated, regardless of ASXL1 mutation status
Yes
No
N/A
Calculate Scores
Risk Category (score)
Survival
MYSEC-PM
-
MYSEC-PM-Mol
-
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